Kisspeptin is a peptide fragment derived from the full-length Kisspeptin (also referred to as Kisspeptin-54 or Metastin). Specifically, Kisspeptin is a fragment containing the 45-54 sequence from the larger parent molecule. Research into this peptide has suggested that the compound may act as a mediator of endocrine signaling between various endocrine cells.

Originating from the KISS1 gene, which is thought to play a critical role in reproductive cell signaling and physiology, Kisspeptin is particularly interesting to researchers for its potential to influence the secretion of gonadotropin-releasing hormone (GnRH). This, in turn, may affect the release of other reproductive hormones from cells with receptors for GnRH. In addition, researchers posit that the compound may potentially impact the development and regulation of blood vessels and renal function, and some studies have suggested it may mitigate cancer cell proliferation and metastasis.